Multiple serotonergic paths to antidepressant efficacy.
نویسنده
چکیده
Depression is a leading cause of disability worldwide. Brain mechanisms underlying the clinical antidepressant efficacy of selective serotonin reuptake inhibitors (SSRI), currently the first-line treatment, remain poorly understood. Recent animal studies have implicated multiple serotonin receptor subtypes in SSRI response, opening new therapeutic perspectives.
منابع مشابه
Neuro Forum Multiple serotonergic paths to antidepressant efficacy
Lutz P.-E. Multiple serotonergic paths to antidepressant efficacy. J Neurophysiol 109: 2245–2249, 2013. First published January 23, 2013; doi:10.1152/jn.01093.2012.—Depression is a leading cause of disability worldwide. Brain mechanisms underlying the clinical antidepressant efficacy of selective serotonin reuptake inhibitors (SSRI), currently the first-line treatment, remain poorly understood....
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ورودعنوان ژورنال:
- Journal of neurophysiology
دوره 109 9 شماره
صفحات -
تاریخ انتشار 2013